| ID | DRAMP00169 |
|---|---|
| Sequence | MAKEFGIPAAVAGTVINVVEAGGWVTTIVSILTAVGSGGLSLLAAAGRESIKAYLKKEIKKKGKRAVIAW |
| Length | 70 |
| Name | Enterocin AS-48 (AS-48; Bacteriocin) |
| Source | Enterococcus faecalis S-48 (Gram-positive bacteria) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacteria: Bacillus subtilus, Bacillus cereus, Bacillus circulans, Bacillus megaterium, Corynebacterium glutamicum, Corynebacterium bovis, Mycobacterium phlei, Nocardia corrallina, Micrococcus luteus, Micrococcus lysodeikticus, Staphylococcus aureus, Streptococcus faecalis, Streptococcus faecium;##Gram-negative bacteria: Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Proteus inconstans, Salmonella typhimurium, Shigella sonnei, Pseudomonas fluorescens, Pseudomonas aeruginosa, Pseudomonas reptilivora. |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | No cytotoxicity information found |
| N-terminal Modification | No specific N-terminal |
| C-terminal Modification | No specific C-terminal |
| Linear/Cyclic/Branched | Cyclic |
| Uniprot | Q47765 |
| PDB | 1E68 ##1O82,1O83,1O84 resolved by X-ray. |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 2501837, 14623193, 11005847 |
Physicochemical Properties
| Residues | 70 |
|---|---|
| Sequence | MAKEFGIPAAVAGTVINVVEAGGWVTTIVSILTAVGSGGLSLLAAAGRESIKAYLKKEIKKKGKRAVIAW |
| Molecular Weight | 7167.462 |
| Grand Average of Hydropathy | 0.549 |
| Isoelectric Point | 10.092 |
| Charge at pH 7.4 | 5.267 |
| Secondary Structure | Helix: 0.343, Turn: 0.214, Sheet: 0.314 |
| Instability Index | 18.819 |
| Aromaticity | 0.057 |