Basic Information
| ID | DRAMP01524 |
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| Sequence | SIRDKIKTIAIDLAKSAGTGVLKTLICKLDKSC |
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| Length | 33 |
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| Name | Rugosin-RN1 (Frogs, amphibians, animals) |
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| Source | Rana nigrovittata |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=4.69 µg/ml), Bacillus subtilis (MIC=9.38 µg/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=25.00 µg/ml);##Yeast: Candida albicans ATCC2002 (MIC=5.63 µg/ml) |
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| Hemolytic Activity | [Ref:19778602]Show weak hemolytic activity against rabbit red cells |
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| Cytotoxicity | [Ref.19778602]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys27 and Cys33) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 19778602 |
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