Basic Information

IDDRAMP01525
SequenceSIRDKIKTIAIDLAKSAGMGILKTLICKLDKSC
Length33
NameRugosin-RN3 (Frogs, amphibians, animals)
SourceRana nigrovittata
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=16.51 µg/ml), Bacillus subtilis (MIC=18.75 µg/ml);##Gram-negative bacterium: Escherichia coli ML-35P (MIC=25.00 µg/ml).##Yeast: Candida albicans ATCC2002 (MIC=15.00 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.19778602]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19778602

Physicochemical Properties

Residues33
SequenceSIRDKIKTIAIDLAKSAGMGILKTLICKLDKSC
Molecular Weight3548.331
Grand Average of Hydropathy0.348
Isoelectric Point9.511
Charge at pH 7.43.191
Secondary StructureHelix: 0.303, Turn: 0.152, Sheet: 0.242
Instability Index7.403
Aromaticity0

Similar Structure Search

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