| ID | DRAMP02422 |
|---|---|
| Sequence | NCIQQCVSKGAQGGYCTNEKCTCY |
| Length | 24 |
| Name | Hlsal-defensin (H. longicornis salivary gland defensin; Ticks, Arthropods, animals) |
| Source | Haemaphysalis longicornis (Bush tick) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-positive bacterium: Staphylococcus aureus (MIC=5-25 mg/mL);##Gram-negative bacterium: Escherichia coli (MIC=10-25 mg/mL). |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | A4GUC4 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 17521774 |
Physicochemical Properties
| Residues | 24 |
|---|---|
| Sequence | NCIQQCVSKGAQGGYCTNEKCTCY |
| Molecular Weight | 2601.933 |
| Grand Average of Hydropathy | -0.492 |
| Isoelectric Point | 7.81 |
| Charge at pH 7.4 | 0.426 |
| Secondary Structure | Helix: 0.167, Turn: 0.250, Sheet: 0.083 |
| Instability Index | 25.558 |
| Aromaticity | 0.083 |