| ID | DRAMP02913 |
|---|---|
| Sequence | GLFGRLRDSLQRGGQKILEKAERIWCKIKDIFRG |
| Length | 34 |
| Name | SMAP-34 (cathelicidin; mammals, animals) |
| Source | Ovis aries (Sheep) |
| Activity | Antimicrobial, Antibacterial |
| Pathogen | [Ref.10768969][No NaCl]: Escherichia coli DH5a (MIC=0.5 μM), Escherichia coli ML-35p (MIC=1.93 μM), Pseudomonas aeruginosa PAO1 (MIC=0.6 μM), Pseudomonas aeruginosa MR3007 (MIC=2 μM), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=4 μM), Staphylococcus aureus 93918 (MIC=1.96 μM).100 mM NaCl: Escherichia coli DH5a (MIC=0.23 μM), Escherichia coli ML-35p (MIC=1.03 μM), Pseudomonas aeruginosa PAO1 (MIC=0.77 μM), Pseudomonas aeruginosa MR3007 (MIC=1.9 μM), Staphylococcus aureus ATCC (MRSA) 33591 (MIC=13.3 μM), Staphylococcus aureus 93918 (MIC=2.13 μM). |
| Hemolytic Activity | [Ref.10768969]30% hemolysis at 1000 μg/ml against human red blood cells. |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 10768969 |
Physicochemical Properties
| Residues | 34 |
|---|---|
| Sequence | GLFGRLRDSLQRGGQKILEKAERIWCKIKDIFRG |
| Molecular Weight | 3988.667 |
| Grand Average of Hydropathy | -0.579 |
| Isoelectric Point | 10.425 |
| Charge at pH 7.4 | 4.526 |
| Secondary Structure | Helix: 0.324, Turn: 0.176, Sheet: 0.206 |
| Instability Index | 27.432 |
| Aromaticity | 0.088 |