Basic Information

IDDRAMP03421
SequenceCSCRTSSCRFGERLSGACRLNGRIYRLCC
Length29
NameNeutrophil antibiotic peptide NP-3 (RatNP-3a, RatNP-3b; Rodents, mammals, animals)
SourceRattus norvegicus (Rat)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiviral
PathogenGram-positive bacterium: Staphylococcus aureus 502A;##Gram-negative bacterium: Escherichia coli ML-35.##Fungi: Candida albicans 820, Cryptococcus neoformans A-383.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationCyclization(Cys1 and Cys29).
C-terminal ModificationCyclization(Cys1 and Cys29).
Linear/Cyclic/BranchedCyclic
Uniprot Q62713, Q9Z1F1
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID2254017, 7594610

Physicochemical Properties

Residues29
SequenceCSCRTSSCRFGERLSGACRLNGRIYRLCC
Molecular Weight3271.826
Grand Average of Hydropathy-0.169
Isoelectric Point9.254
Charge at pH 7.44.409
Secondary StructureHelix: 0.207, Turn: 0.276, Sheet: 0.172
Instability Index37.39
Aromaticity0.069

Similar Structure Search

Candidates based on structure

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