| ID | dbAMP00637 |
|---|---|
| Sequence | ATCYCRTGRCATRESLSGVCRISGRLYRLCCR |
| Length | 32 |
| Name | Human Defensin-5, HD5 [E21R]&&Human alpha defensin |
| Source | Human alpha defensin |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus ATCC 25923 (LD90=2.2±0.6µg/ml)&&Staphylococcus aureus ATCC 25923 (LD50=0.6±0.4µg/ml)&&Jurkat LTR-GFP Cells (JLTRG) &&HSV-2 (IC50 P=25µg/ml)&&HIV-1 HTLV-IIIB (IC50=3.53µg/ml)&&Herpes simplex virus 2&&Escherichia coli ATCC 25922 (LD90= |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | Q01523 |
| PDB | 4RBX |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 23269800, 25782105 |
Physicochemical Properties
| Residues | 32 |
|---|---|
| Sequence | ATCYCRTGRCATRESLSGVCRISGRLYRLCCR |
| Molecular Weight | 3615.248 |
| Grand Average of Hydropathy | -0.144 |
| Isoelectric Point | 9.486 |
| Charge at pH 7.4 | 5.457 |
| Secondary Structure | Helix: 0.219, Turn: 0.188, Sheet: 0.188 |
| Instability Index | 7.769 |
| Aromaticity | 0.062 |