Basic Information

IDDRAMP03410
SequenceVTCFCRRRGCASRERLIGYCRFGNTIYGLCCRR
Length33
NameNeutrophil defensin 3 (HANP-3; alpha-defensin; Rodents, mammals, animals)
SourceMesocricetus auratus (Golden hamster)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis;##Gram-negative bacteria: Escherichia coli, Salmonella serotype krefeld, Klebsiella oxytoca, Pseudomonas aeruginosa.##Fungi: Candida albicans, Cryptococcus neoformans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P81467
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8890190

Physicochemical Properties

Residues33
SequenceVTCFCRRRGCASRERLIGYCRFGNTIYGLCCRR
Molecular Weight3890.599
Grand Average of Hydropathy-0.188
Isoelectric Point9.8
Charge at pH 7.46.372
Secondary StructureHelix: 0.273, Turn: 0.182, Sheet: 0.121
Instability Index52.17
Aromaticity0.121

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