Basic Information

IDDRAMP03333
SequenceSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS
Length35
NameAlpha-defensin cryptdin-5 (Defensin-related cryptdin5; Rodents, mammals, animals)
SourceMus musculus (Mouse)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Listeria monocytogenes EGD;##Gram-negative bacteria: Escherichia coli ML-35p, mouse-avirulent Salmonella typhimurium 7953.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P28312, Q64382
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID1500431

Physicochemical Properties

Residues35
SequenceSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS
Molecular Weight4208.104
Grand Average of Hydropathy0.12
Isoelectric Point9.861
Charge at pH 7.47.097
Secondary StructureHelix: 0.343, Turn: 0.143, Sheet: 0.114
Instability Index35.169
Aromaticity0.143

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