| ID | dbAMP00633 |
|---|---|
| Sequence | ATCYCRRGRCATRESLSGVCRISGRLYRLCCR |
| Length | 32 |
| Name | Human Defensin-5, HD5 [T7R,E21R] |
| Source | |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus ATCC 25923 (LD90=1.4±0.3µg/ml)&&Staphylococcus aureus ATCC 25923 (LD50=<0.39µg/ml)&&Escherichia coli ATCC 25922 (LD90=1.8±0.4µg/ml)&&Escherichia coli ATCC 25922 (LD50=0.8±0.3µg/ml) |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | Q01523 |
| PDB | 4RBW |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 25782105 |
Physicochemical Properties
| Residues | 32 |
|---|---|
| Sequence | ATCYCRRGRCATRESLSGVCRISGRLYRLCCR |
| Molecular Weight | 3670.329 |
| Grand Average of Hydropathy | -0.263 |
| Isoelectric Point | 9.801 |
| Charge at pH 7.4 | 6.457 |
| Secondary Structure | Helix: 0.219, Turn: 0.188, Sheet: 0.188 |
| Instability Index | 25.669 |
| Aromaticity | 0.062 |