Basic Information
| ID | DRAMP03510 |
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| Sequence | KWKLFKKIEKVGQNIRDGIIKAGPAVAVVGQATQIAK |
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| Length | 37 |
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| Name | Cecropin A |
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| Source | Hyalophora cecropia |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.7140755] Gram-negative bacterium: Escherichia coli D21 (LC=0.19 µM), Escherichia coli D31 (LC=0.21 µM), Serratia marcescens Db11 (LC=4.2 µM), Serratia marcescens Db1108 (LC=2.5 µM), Serratia marcescens Db1121 (LC=4.4 µM), Serratia marcescens Strain 122 (LC=3.2 µM), Pseudomonas aeruginosa OT97 (LC=4.8 µM), Xenorhabdus nematophilus Xn21 (LC=1.4 µM).##[Ref.29925795]Gram-negative bacterium:Escherichia coli CVCC 245 (MIC=4.2 ± 0.35μg/mL);##Gram-positive bacteria:Staphylococcus aureus ATCC 25923 (MIC=198 ± 10.1μg/mL),L. mono. CVCC 1599 (MIC=64.5 ± 3.20μg/mL) |
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| Hemolytic Activity | [Ref.29925795] 50% hemolysis at 169 ± 8.20 μg/ml against sheep red blood cells. |
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| Cytotoxicity | [Ref.29925795]No cytotoxicity information found##[Ref.7140755]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P01507 |
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| PDB |
1D9J |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 7140755, 29925795 |
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