Basic Information

IDDRAMP03573
SequenceIGKEFKRIVQRIKDFLRNLVPRTES
Length25
NameLL-37(13-37)(C-terminal fragment of LL-37; Human, mammals, animals)
SourceHomo sapiens (Human)
ActivityAntimicrobial, Antibacterial, Anti-Gram-, Anticancer
PathogenGram-negative bacterium: Escherichia coli K12 (MIC=80 µM).##Drug-resistant KBv cancer cells (LC50=39 µM), Drug-sensitive KB cancer cells (LC50=40 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P49913, Q71SN9
PDB 2FCG
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16637646

Physicochemical Properties

Residues25
SequenceIGKEFKRIVQRIKDFLRNLVPRTES
Molecular Weight3043.568
Grand Average of Hydropathy-0.624
Isoelectric Point10.932
Charge at pH 7.43.553
Secondary StructureHelix: 0.360, Turn: 0.160, Sheet: 0.160
Instability Index36.16
Aromaticity0.08

Similar Structure Search

Candidates based on structure

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