Basic Information
| ID | DRAMP03599 |
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| Sequence | GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK |
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| Length | 45 |
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| Name | Human beta-defensin 3 (BD-3, hBD-3; Hbd3; Beta-defensin 103; Human, mammals, animals) |
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| Source | Homo sapiens (Human) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.11085990]Gram-negative bacteria: Escherichia coli DSM1103 (MIC=9.4 µg/ml), Klebsiella pneumoniae DSM681 (MIC=25 µg/ml), Pseudomonas aeruginosa DSM1128 (MIC=18.75 µg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=4.7 µg/ml), Streptococcus pneumoniae DSM11865 (MIC=4.7 µg/ml). |
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| Hemolytic Activity | [Ref.11085990] It has 9% hemolysis at 250 µg/ml, 15% hemolysis at 500 µg/ml against human erythrocytes. |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P81534, Q8NFG6, Q9NPF6 |
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| PDB |
1KJ6 |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15625724, 11085990 |
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