| ID | DRAMP18618 |
|---|---|
| Sequence | RGLRRLGRKIAHGVKKY |
| Length | 17 |
| Name | SMAP-29(1-17) (SMAP-29 peptide derivative) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anitifungal |
| Pathogen | [Ref.11467858]Gram-positive bacteria: [No NaCl]: Bacillus subtilis (MIC=8.0 μM), Staphylococcus aureus (MIC=2.0 μM), Micrococcus luteus (MIC=2.0 μM), Staphylococcus epidermidis (MIC=1.0 μM);##[100 mM NaCl]: Bacillus subtilis (MIC=16.0 μM), Staphylococcus aureus (MIC=4.0 μM), Micrococcus luteus (MIC=4.0 μM), Staphylococcus epidermidis (MIC=2.0 μM).##Gram-negative bacteria: [No NaCl]: Escherichia coli (MIC=8.0 μM), Salmonella typhimurium (MIC=2.0 μM), Pseudomonas aeruginosa (MIC=8.0 μM);[100 mM NaCl]: Escherichia coli (MIC=16.0 μM), Salmonella typhimurium (MIC=8.0 μM), Pseudomonas aeruginosa (MIC=16.0 μM).##Fungi: [No NaCl]: Candida albicans (MIC=8.0 μM);[100 mM NaCl]: Candida albicans (MIC=16.0 μM). |
| Hemolytic Activity | [Ref.11467858]Non-hemolysis at 100 μM against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 11467858 |
Physicochemical Properties
| Residues | 17 |
|---|---|
| Sequence | RGLRRLGRKIAHGVKKY |
| Molecular Weight | 2008.423 |
| Grand Average of Hydropathy | -1.018 |
| Isoelectric Point | 12 |
| Charge at pH 7.4 | 6.584 |
| Secondary Structure | Helix: 0.294, Turn: 0.176, Sheet: 0.176 |
| Instability Index | 31.659 |
| Aromaticity | 0.059 |
