Basic Information

IDDRAMP18664
SequenceANFLPKIFCKITRKC
Length15
NameBrevinin 15 (Brevinin-1E truncated peptide 15; Frogs, amphibians, animals)
SourceRana esculenta
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anitifungal, Anti-Gram-
Pathogen[Ref.9748603]Gram-positive bacteria: Staphylococcus aureus ATCC 6538 (MIC=100 μg/ml), Micrococcus luteus ATCC 9341 (MIC=25 μg/ml);##Gram-negative bacteria: Escherichia coli ATCC 2592 (MIC=50 μg/ml), Pseudomonas aeruginosa ATCC 9027 (MIC=50 μg/ml);##Fungus: Candida albicans ATCC 36232 (MIC=50 μg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9748603

Physicochemical Properties

Residues15
SequenceANFLPKIFCKITRKC
Molecular Weight1782.224
Grand Average of Hydropathy0.213
Isoelectric Point9.851
Charge at pH 7.43.551
Secondary StructureHelix: 0.333, Turn: 0.133, Sheet: 0.133
Instability Index0.833
Aromaticity0.133

Similar Structure Search

Candidates based on structure

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