Basic Information

IDDRAMP21178
SequenceGILSSLWKKLKKWIAK
Length16
NameHYL-25 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=2.5 μM), Staphylococcus epidermidis(MIC=1.6 μM);##Gram-negative bacteria : Escherichia coli(MIC=2.5 μM), Pseudomonas aeruginosa 5482(MIC=13 μM);##Fungi : Candida albicans(MIC=13 μM)
Hemolytic Activity[Ref.26998557] LC50=57 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
SequenceGILSSLWKKLKKWIAK
Molecular Weight1899.368
Grand Average of Hydropathy-0.069
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.438, Turn: 0.188, Sheet: 0.250
Instability Index32.331
Aromaticity0.125

Similar Structure Search

Candidates based on structure

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