Basic Information

IDdbAMP03491
SequenceGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR
Length32
NameMus musculus&&DEFA4_MOUSE&&Cyclized Alpha-defensin 4, Cyclized Cryptdin-4, Crp4-1&&Crp4-wt&&Alpha-defensin 4, Cryptdin-4
SourceMus musculus
ActivityAntibacterial
PathogenStaphylococcus aureus EB378 (90-100% Killing=10µg/ml)&&Staphylococcus aureus ATCC BAA-39 (MIC=>16µM)&&Staphylococcus aureus ATCC BAA-39 (MIC=1-2µM)&&Staphylococcus aureus ATCC 43300 (MIC=8µM)&&Staphylococcus aureus ATCC 43300 (MIC=2µM)&&Staphylococcus aur
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P28311
PDB 2GW9&&1TV0&&2GW9&&2GWP&&2LEW&&2LEY&&1TV0&&2GW9
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22040603, 22040603, 22040603, 22040603, 22040603, 15595831, 15489334

Physicochemical Properties

Residues32
SequenceGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR
Molecular Weight3761.528
Grand Average of Hydropathy-0.469
Isoelectric Point9.86
Charge at pH 7.47.438
Secondary StructureHelix: 0.250, Turn: 0.188, Sheet: 0.125
Instability Index25.816
Aromaticity0.094

Similar Structure Search

Candidates based on structure

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