Basic Information

IDdbAMP10922
SequenceSCTCRRAWICRWGERHSGKCIDQKGSTYRLCCRR
Length34
NamePaneth cell-specific alpha-defensin 1, DEFA1&&Equus caballus&&A6YB85_HORSE
SourceEquus caballus
ActivityAntibacterial
PathogenStreptococcus pyogenes ATCC 12344 (MBC=0.8µM)&&Streptococcus pyogenes ATCC 12344 (LD90=0.8µM)&&Staphylococcus epidermidis ATCC 14990 (MBC=1.5µM)&&Staphylococcus epidermidis ATCC 14990 (LD90=0.8µM)&&Staphylococcus aureus ATCC 6538 (MBC=0.8µM)&&Staphylococc
Hemolytic ActivityNot included yet
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A6YB85
PDB 2MXQ
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17620056

Physicochemical Properties

Residues34
SequenceSCTCRRAWICRWGERHSGKCIDQKGSTYRLCCRR
Molecular Weight4076.724
Grand Average of Hydropathy-0.926
Isoelectric Point9.69
Charge at pH 7.46.137
Secondary StructureHelix: 0.176, Turn: 0.176, Sheet: 0.088
Instability Index69.853
Aromaticity0.088

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.