Basic Information

IDDRAMP02317
SequenceFIGLLISAGKAIHDLIRRRH
Length20
NameChrysophsin-3 (fish, chordates, animals)
SourceChrysophrys major (Red sea bream)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.12581207]Gram-positive bacteria: Bacillus subtilis ATCC 6633 (MIC=0.25 µM), Lactococcus garvieae ATCC 49156 (MIC=10 µM), S.iniae F-8502 (MIC=10 µM);##Gram-negative bacteria: Escherichia coli WT-2 (MIC=0.25 µM), Vibrio anguillarum ATCC 19264 (MIC=10 µM), Vibriopenaeicida KHA (MIC=10 µM), V. harveyi ATCC 14126 (MIC=5 µM), V. vulnificus ATCC 33148 (MIC=10 µM), Aeromonas salmonicida NCMB 1102 (MIC=10 µM), Pseudomonas putida ATCC 12633 (MIC=40 µM).
Hemolytic Activity[Ref.12581207]0% hemolytic activity at 0.25 μM, 10% hemolytic activity at 1 μM against human erythrocytes.
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83547
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12581207

Physicochemical Properties

Residues20
SequenceFIGLLISAGKAIHDLIRRRH
Molecular Weight2286.723
Grand Average of Hydropathy0.345
Isoelectric Point11.711
Charge at pH 7.42.629
Secondary StructureHelix: 0.400, Turn: 0.150, Sheet: 0.250
Instability Index78.335
Aromaticity0.05

Similar Structure Search

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