| ID | DRAMP02437 |
|---|---|
| Sequence | GFWKKVGSAAWGGVKAAAKGAAVGGLNALAKHIQ |
| Length | 34 |
| Name | Papillosin |
| Source | Halocynthia papillosa (Red sea-squirt) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.19085906]Gram-positive bacteria (Native, Synthetic): Micrococcus luteus A270 (MBC=0.13-0.25, 0.19-0.39 µM), Aerococcus viridans 54.145 T (MBC=ND, 0.19-0.39 µM), Bacillus megaterium 66.20 T (MBC=ND, 0.05-0.10 µM), Staphylococcus aureus 65.8 T (MBC=0.5-1.00, 1.56-3.13 µM), Enterococcus faecalis 103015 T (MBC=ND, 0.78-1.56 µM);##Gram-negative bacteria (Native, Synthetic): Enterobacter aerogenes 30.86 T (MBC=ND, 0.78-1.56 µM), Pseudomonas aeruginosa 100720 T (MBC=ND, 3.13-6.25 µM), Salmonella thyphimurium 60.62 T (MBC=ND, 0.78-1.56 µM), Klebsiella pneumoniae 82.91 T (MBC=ND, 0.39-0.78 µM), Escherichia coli (MBC=0.25-0.50, 0.78-1.56 µM) |
| Hemolytic Activity | [Ref.19085906]0% hemolytic activity at 50 μM against sheep erythrocytes |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P86416 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 19085906 |
Physicochemical Properties
| Residues | 34 |
|---|---|
| Sequence | GFWKKVGSAAWGGVKAAAKGAAVGGLNALAKHIQ |
| Molecular Weight | 3320.845 |
| Grand Average of Hydropathy | 0.253 |
| Isoelectric Point | 10.602 |
| Charge at pH 7.4 | 4.582 |
| Secondary Structure | Helix: 0.265, Turn: 0.265, Sheet: 0.324 |
| Instability Index | 13.506 |
| Aromaticity | 0.088 |