Basic Information

IDDRAMP03169
SequenceRARAPHKAWYNCMTDAGISGAIAGAVAGCAATIEIGCVEGAIAGIGPSGIASMIAALWTCRSKY
Length64
NameProtease-activated antimicrobial peptide
SourcePropionibacterium jensenii
ActivityAntimicrobial, Antibacterial
PathogenPropionibacterium acidipropionici ATCC 4965 (MIC=3.6 nM), P. acidipropionici ATCC 4875 (MIC=7.2 nM), P. acidipropionici (MIC=3.6 nM), P. freudenreichii subsp. freudenreichii ATCC 6207T (MIC=7.2 nM), P. freudenreichii INF-P203 (MIC=116 nM), P. freudenreichii INF-P205 (MIC=58 nM), P. jensenii LMG 2820 (MIC=116 nM), P. jensenii LMG 3032 (MIC=116 nM), P. thoenii INF-P410 (MIC=116 nM), P. thoenii INF-P414 (MIC=0.9 nM), Lactobacillus delbrueckii subsp. lactis ATCC 4797 (MIC=0.5 nM), L. delbrueckii subsp. lactis DSM 20072T (MIC=0.2 nM), L. delbrueckii subsp. bulgaricus DSM 20081T (MIC=7.2 nM), L. helveticus DSM 20075T (MIC=0.9 nM), Lactobacillus plantarum LMG 2003 (MIC=116 nM), L. sakei NCDO 2714 (MIC=0.9 nM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12057960

Physicochemical Properties

Residues64
SequenceRARAPHKAWYNCMTDAGISGAIAGAVAGCAATIEIGCVEGAIAGIGPSGIASMIAALWTCRSKY
Molecular Weight6383.366
Grand Average of Hydropathy0.531
Isoelectric Point8.504
Charge at pH 7.41.489
Secondary StructureHelix: 0.234, Turn: 0.250, Sheet: 0.312
Instability Index32.711
Aromaticity0.062

Similar Structure Search

Candidates based on structure

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