Basic Information

IDDRAMP03285
SequenceLFCRKGTCHFGGCPAHLVKVGSCFGFRACCKWPWDV
Length36
NameOstricacin-1 (Beta-defensin 2; Birds, animals)
SourceStruthio camelus (Ostrich)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus 1056-MRSA (MIC=1.25 µg/ml), S. aureus NCTC 4163 (MIC=6.7 µg/ml);##Gram-negative bacteria: Escherichia coli O157:H7 (MIC=0.96 µg/ml), E. coli 0111 (MIC=6.7 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot P85113
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16459058

Physicochemical Properties

Residues36
SequenceLFCRKGTCHFGGCPAHLVKVGSCFGFRACCKWPWDV
Molecular Weight4017.774
Grand Average of Hydropathy0.303
Isoelectric Point8.94
Charge at pH 7.43.477
Secondary StructureHelix: 0.306, Turn: 0.222, Sheet: 0.111
Instability Index37.894
Aromaticity0.167

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