Basic Information

IDDRAMP03567
SequenceKRIVQRIKDFLRNLVPRTES
Length20
NameKR-20 (Derived from LL-37)
SourceHomo sapiens (Human sweat)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus mprF (MIC=16 µM), Staphylococcus aureus ATCC 25923 (MIC>64 µM), Staphylococcus aureus (GAS) (MIC=4 µM);##Gram-negative bacterium: Escherichia coli O29 (MIC>64 µM).##Yeast: Candida albicans ATCC 14053 (MIC=10 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID14978112

Physicochemical Properties

Residues20
SequenceKRIVQRIKDFLRNLVPRTES
Molecular Weight2468.899
Grand Average of Hydropathy-0.755
Isoelectric Point11.554
Charge at pH 7.43.554
Secondary StructureHelix: 0.350, Turn: 0.150, Sheet: 0.150
Instability Index54.46
Aromaticity0.05

Similar Structure Search

Candidates based on structure

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